Research

Pharmacotherapy effects on smoking cessation vary with nicotine metabolism gene (CYP2A6) – Addiction. A study on genetic factors understood to influence nicotine metabolism found that genetic differences in a sample of 709 smokers of European ancestry were associated with the effectiveness of nicotine replacement therapy in smoking cessation. The authors hope that continued genetic research in tobacco will one day allow for personalized smoking cessation interventions.

Crowdsourced peer- versus expert-written smoking-cessation messages – American Journal of Preventive Medicine. A two-phase study in which researchers collected smoker-to-smoker (S2S) messages and then disseminated them to smokers via e-mail as part of the Decide2Quit.org tobacco intervention, found that the peer-written S2S messages were more likely than expert messages to facilitate a return visit to the website.

Trends in smoking before, during, and after pregnancy — Pregnancy Risk Assessment Monitoring System, United States, 40 Sites, 2000–2010 – Morbidity and Mortality Weekly Report (MMWR). An assessment of data from 40 sites of the state-based Pregnancy Risk Assessment Monitoring System (PRAMS) has found that efforts to reduce smoking prevalence among female smokers before pregnancy have not been effective. However, tobacco control efforts have been minimally effective in reducing smoking prevalence during and after pregnancy. The researchers note that sustained and comprehensive state tobacco control efforts are needed to help reduce prevalence.

Automated tobacco assessment and cessation support for cancer patients – Cancer. A study involving 2,765 cancer patients who were also tobacco users concluded that an automated electronic health record-based tobacco assessment and cessation referral program can identify substantial numbers of smokers who are receptive to enrollment in a cessation support service.

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